I have taken elk here in WY with a .45,,50 and a 54. Huge difference between the .45 and the 54. With a .45, a double lung at 40 yards, the elk took off running. No reaction that he had been hit. Tracked for over 400 yards,,, spotted him on the next hillside. Trying to go uphill but was unable to. Just stood there with his dead down. By the time we got close enough for another shot, it was obvious he was going nowhere. At 30 yards another shot finished him off. No blood trail, just his hoof prints digging into the ground as he ran. If we had not spotted him, it would have been at least another day before we could have found him. 54 on the other hand it was obvious he had been hit. THUMP!! That is the sound of the round ball hitting him. 60 yards and he went about 30 yards and staggered over backwards and was dead before we got to him. If my life depended on shooting an elk with a .45 cal, I would do it but I use nothing but my .54 now. Although two years ago I packed my 62 cal fowler but never even seen an elk that was approachable,,,, I don't shoot at elk over 100 yards with my .54 and not over 50 yards with the fowler.