since this is a swamped barrel, you're pretty much stuck with the location of the barrel/tang combination without trying to tinker with the curve in the stock into which the swamped barrel fits.
it is, what it is.
therefore, the location of the barrel pretty much 'drives the train' as to the location of the lock. hopefully, the whole deal has been done properly, and the lock will be in such a position that the touch hole will be about 3/16 to 1/4 forward of the face of the breech. to check this, i would assemble the barrel and breech and do the final inlet of them as one unit. mark the breech face by dropping the ramrod down the barrel and making a pencil mark at the muzzle, then put the rod next to the barrel and see where the end goes. the end of the rod will be the beginning of the breech face, of course. then you know where you need the touch hole to go.
you want the touch hole to be centered in the pan, and ever so slightly above the top edge of the pan. if this doesn't line up, two things will happen: it will look funny (and therefore bug the #$*@ out of you whenever you see it) and (more important) it will not work as well. the further away from the "sunset position" it is, the worse it will look, and the less likely you are to get good performance from your lock.
you can, of course, cut a groove into the breech face, so that the flash from the touch hole can ignite your powder. i understand that this has been done on some original rifles. don't get too carried away, and try to keep the cut as smooth as possible. be aware, of course, the if you start to really cut back on the breech, you are weakening the whole system: use good common sense.
i have made rifles from both pre- carved stocks and from blanks. the problems with a precarve (as outlined above) is why i prefer to do a blank, but that doesn't mean that precarves are shoddy or substandard in any way: they can save a boatload of time and frustration of done correctly. I wouldn't hesitate, for instance, to use a Pecatonica pre- carve: their geometry is spot on. depends on how much of the woodwork you want to do yourself.
hope this helps
good luck with your project - go slow, 'sneak up on it' (it's a journey, not a race) and when you're all done
Make Good Smoke!