When the TH diameter gets above 5/64", you see a measurable drop in velocity, but its not so much that its worth worrying about. I don't know anyone who has bothered to investigate it, either. When I set up my flintlock- long before I owned a chronograph, I simply watched for a drop in the POI at 50 yds when I was opening the TH in my Chamber's White Lightning vent liner.
I do think the White Lightning vent line, having a parabolic CONE on the inside of the liner, uses escaping gases to keep other gases in check for a few microseconds, until the ball is moving. It does this by focusing gases and pushing them back towards the bore, during firing, slowing the escape of gases, uniformly.
Most liners come with a 1/16" or smaller hole in them. You can use either 3Fg or 2Fg powder in the barrel and get good consistency in your MVs. When you get over 1/16",some 3Fg powder will come out the TH, while most 2fg powder granules won't.
If you are only plinking, or hunting with your flintlock, the choice of TH liners simply won't be noticed. It is noticed by the serious Target shooters, however. Its the target shooters who have told everyone all the glowing reports about the Chamber's designed, White Lightning liners.