i have a .45 pedersoli kentucky. using 2fg, start with at least 60 grains. once you get the patch thickness sussed out, increase 5 grains at a time and shoot 5 balls for each. with good weather and careful bench shooting, you'll find a charge load yer rifle will like best. make SURE to run a lightly lubed patch down and out ONCE between each firing to keep the fouling soft.
fwiw, 75 grains of 2fg works best in my pk, but all these rifles are different and yers might like a tad more or less. this is the fun part, getting to know yer rifle and figuring out a consistently accurate load.
enjoy, be safe, and have a ball!