grnmt
The "current" Pedersoli double rifles are "regulated" at the factory with lasers...so you are correct, they don't do it the old fashioned way. Nor, have they been able to consistently produce a double rifle that shoots to the "same" point of aim with each barrel, given the same load/projectile.
One can tweak the loads in one barrel to come close, but will often mean a different powder charge in one over the other. The current centerfire double rifle made by Pedersoli does a pretty good job of putting rounds from each barrel into a 4" circle at 50 yards using individual sights. However, when the gun originally came out and could be purchased for a measily $1600, the two sets of sights were mounted one for each barrel. The one not being used could be flipped down.
I haven't heard of any muzzle-loaders, who could get both barrels to shoot to point of aim with one sight, using the same bullet/powder combo in each barrel. Perhaps there have been a few, but I've not spoken to any, or read an account of one. Every account I've read indicated that one barrel had to have a different powder charge than the other and in some cases a different bullet weight, to bring the impact points into usable approximation with the same set of sight.
Regards
Dan