On the hybrid rifle that I built, the "snail" breech was threaded 5/8-18, and the internal "cone" was done with a 9/32 ball endmill on the lathe in a 4 jaw chuck at 115 rpm.
Depth of penetration is dictated by the channel from the nipple cavity into the "chamber".
The drill diameter should be within the span between .1065 (small) to .144 (large), as this is the span I have seen in working configurations thus far, of course, there has to be variances beyond this span, but this is just what I have seen.
The hole connecting the nipple allocation and the "chamber" is drilled at an angle to intersect at the target location. Put the breechplug in a vise on the drillpress if you can.
I drilled the connecting hole to intersect the 9/32 diameter chamber at the base, and if I run a pipe cleaner through the channel, the "fuzz" of the cleaner will brush against the rearmost curvature of the semispherical 9/32 diameter chamber.
With the 5/8-18 breechplug (.700" thread penetration) a 9/32" diameter "chamber" will have no ill effects. The chamber (if memory serves me correctly) was about .400" to .450" deep.
If the breechplug was 3/4" (threaded portion) a 5/16" ball endmill would be fine.
These figures represent a very safe setup, you could go larger in all directions, but I do not think that it is required.