Why ream it out and to what diameter? The originals were 54 cal, the Pedersoli is about 58 cal, so you can't ever make it like the original.
The Pedersoli Harpers Ferry is a fairly nice flinter, but with some lock geometry issues, plus most new versions require you to grind the back side of the flint to assure the half-cock does not sit on the frizzen.
You would need to find someone with a lathe, the ability to remove the breech plug without damaging the barrel, a reamer to remove the rifling (maybe 0.590" or so), a polishing scheme to remove the reamer chatter marks, and now what have you got?
If you like Harpers Ferry 1803 pistols, be prepared to spend some $$$$ with a custom builder to get a modern replica. It will be historically accurate, not an Italian "almost" version.
I'd leave it alone and save my $$$.