My Lyman's black powder handbook states the following for the 1851 Colt Navy loads...
.375 grain round ball (81 grains) and #11 percussion caps.
14.0 grains FFFg = 752 fps velocity
17.0 grains FFFg = 879 fps velocity
20.0 grains FFFg = 967 fps velocity
23.0 grains FFFg = 1017 fps velocity
26.0 grains FFFg = 1079 fps velocity
29.0 grains FFFg = 1097 fps velocity
*The Lyman load book also states that 29.0 grains is the maxium cahrge for a round ball in this revolver*
Lyman projectile #37583 (150 grains) and #11 percussion caps.
9.0 grains FFFg = 480 fps velocity
12.0 grains FFFg = 560 fps velocity
15.0 grains FFFg = 668 fps velocity
*15.0 grains being the max load for this bullet*
Do not forget to cover the bullets in the cylinder with lube to help prevent chain fires.
Here is a link on cleaning the 1851 navy...
http://www.civilwarguns.com/0210.html
NAVY ARMS 1851 NAVY COLT/.375" SPEER RB/REMINGTON #11 CAPS
20 gr. Pyrodex P
Ox-Yoke Wad
624 velocity
25 gr. Pyrodex P
Crisco lube
1084 velocity