It's usually the presence of powder fouling or other salts that allows moisture cling and start rust.
An older barrel that has already been subject to even surface rust will be problematic, once it's started it's a constant battle.
This is one of the troubles you'll face with your "matchlock" barrel, crud builds in the right angle drum area of the cva drum breech style barrels, by plugging the end with a vent and making it non-removable you've made it very difficult to clean in that area.
Any oils left in that spot is really a problem, When oil is mixed with heat and powder fouling it turns into a HARD tar like substance that plugs the flash channel. This is why OILS need to be cleaned completely from an ML bore before it's fired.
Many people leave ML's loaded for extended hunting periods with no harm to the bore