As the others have said yes. A few points to consider for determining if you should. Which eye dominate are you left or right. Left eye dominate is preferred to shooting lefty and both eyes open. With R guns, pan flash may be an issue. Easily over come with a blinder patch, darkened glasses, shut the right eye etc. I naturally shot lefty, and wear safety glasses (shooting glasses) with a disc of opaque scotch tape in the center of the R lens. I wear these glasses all the time whether using L or R sided guns especially with flinters. Have had an incident where a flint shard or powder spray gets caught in the eyes. Nasty business then.