20 to 40 grs for target. 50 to 60grs for deer. Shot two deer with a .45 round ball. Ball on both deer completely penetrated the deer and kept going. Broadside shots in the lungs. Both shots were .440" balls pushed by 60grs of Goex ffg. One was at 10 yards+/- . The other was 50ish yards. I would keep shots to 75 yards or less.
Btw- I have found that Spanish barrels can be very accurate barrels.