Huh....
I haven't had any issues with REAL, TC Maxis and Minis, factory Hornady GPs or the Lyman homecast version in my 54 Hunter barrel, so I haven't done much testing beyond initial load development. Just load and start having fun. Only consistent rule seemed to be that it needed minimum charges of 80 grains of 2f to tighten up, but more got better and better. I valued the fillings in my teeth and didn't want them falling out, so I settled on 90 grains with REAL and TC, 100 grains with Hornady and Lyman.
Only other consistent "rule" was to put a lubed felt wad between the powder and the bullet.
Haven't popped any game at all with any of them cuzz I keep on using round ball for that. But I've sure shot a lot of conicals over the years, mostly "mortar" fire well past 100 yards. That big ole conical makes a bigger gout of dirt than round ball when it lands, usually making it easier to see where it hit so I can adjust elevation on the next shot.